Quiz: How many did you get?

Debaditya Roy MD
DM Resident, Department of Clinical Immunology and Rheumatology, Institute of Postgraduate Medical Education and Research (IPGMER), Kolkata

1. Normal Thymus can be visualized in which type of SCID?

a. CD45 deficiency
b. Coronin Deficiency
c. DNA ligase IV deficiency
d. DNA PK deficiency

2. Hypertrophic Pulmonary Osteoarthropathy can develop in HIV infected patients especially in association with

a. Mycobacterium tuberculosis
b. Pneumocystis jirovecii
c. Staphylococcus aureus
d. Neisseria gonorrhoeae

3. Most classic pattern of brain lesions in Susac Disease?

a. Parenchymal
b. Periventricular
c. Pericallosal
d. Meningeal

4. Satoyoshi Syndrome all are true Except

a. Characteristic muscle spasms especially facial muscles
b. Diarrhoea
c. Amenorrhoea
d. Alopecia

5.ROSAH syndrome is a newly described NF kB mediated autoinflammatory disease; All are true about it except:

a. Retinal Dystrophy
b. Splenomegaly
c. Anhidrosis
d. Autosomal Recessive

6.Type A and B synoviocytes in RA synovium shows an increased staining with

a. CD 55 and CD 65
b.CD60 and CD 52
c.CD 68 and CD 55
d. CD 52 and CD 62

7. Nucleobindin-2 pattern in ANA is associated with all Except?

a. Polymyositis
b. Systemic Sclerosis
c. SLE
d. Sjogrens Syndrome

8. Sparsentan is a novel drug approved recently by FDA for use in

a. Systemic Sclerosis PAH
b. Severe Combined Immunodeficiency
c. IgA nephropathy
d. MDA5 Dermatomyositis

9.Most common mutation implicated in causing CANDLE syndrome:

a. PSMB8

10. “ The ARIAA- – study“ is associated with

a. APS and Apixaban
b. SLE and Anifrolumab
c. Psoriatic Arthritis and Anifrolumab
d. RA and Abatacept

11. Hajdu Cheney Syndrome is a rare monogenic disorder characterized by all Except

a. Mutations in NOTCH1
b. Delayed speech and motor skills
c. Short stature
d. Treated by Bisphosphonates

Answer Key:

01. B Coronin Deficiency
02. B Pneumocystis jiroveci
03. C Pericallosal
04. A Characteristic muscle spasms usually facial muscles (Correct: usually spares facial muscles)
05. D Autosomal Recessive (Correct: Autosomal Dominant)
06. C CD 68 and CD 55
07. D Sjogrens Syndrome
08. C IgA Nephropathy
09. A PSMB8
10. D RA And Abatacept
11. A Mutations in NOTCH1 (Correct: Mutations in NOTCH2)